منابع مشابه
How toxic is ibogaine?
CONTEXT Ibogaine is a psychoactive indole alkaloid found in the African rainforest shrub Tabernanthe Iboga. It is unlicensed but used in the treatment of drug and alcohol addiction. However, reports of ibogaine's toxicity are cause for concern. OBJECTIVES To review ibogaine's pharmacokinetics and pharmacodynamics, mechanisms of action and reported toxicity. METHODS A search of the literatur...
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The database research community has been building methods to store, access, and update data for more than four decades. Throughout the evolution of the structures and techniques used to access data, access methods adapt to the ever changing hardware and workload requirements. Today, even small changes in the workload or the hardware lead to a redesign of access methods. The need for new designs...
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Background: Radiotherapy and adjuvant androgen deprivation therapy have historically been the first treatment choices for prostate cancer but treatment resistance often limits the capacity to effectively manage the disease. Therefore, alternative therapeutic approaches are needed. Here, the efficacies of radiotherapy and targeting the pro-survival cell signaling components epidermal growth fact...
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Parkinson's disease (PD) is one of the neurodegenerative diseases which we can by certainty identify its pathology, however, this confidence disappeares when talking about the cause. A long history of trials, suggestions, and theories tried linking PD to a specific causation. In this paper, a new suggestion is trying to find its way, could it be toxicology? Can we-in the future-look to PD as an...
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The plasticizer di(2-ethylhexyl)phthalate (DEHP) used in peritoneal dialysate bags is known to dissolve into the solution, even though the quantity is small. Long-term exposure of the peritoneum to DEHP could be a cause of peritoneal deterioration. Although some papers have been published about DEHP toxicity to the peritoneum, acute DEHP toxicity is not fully understood to date. We therefore co...
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ژورنال
عنوان ژورنال: Annales de Toxicologie Analytique
سال: 2008
ISSN: 0768-598X,1961-9480
DOI: 10.1051/ata/2009010